Welcome to an exciting year of AP Bio! The workload will be demanding, but shouldn't overwhelm you IF you stay on top of assignments. Rule of thumb: for every hour you spend in class, you should devote two hours outside of class studying. We'll also have many islands of fun during our year of discovering the wonders of biology (AP babies, Darwin's birthday party, DNA Day!).
No upcoming assignments.
Epigenetics, Imprinting and Barr body formation all involve some form of nucleosome modification mediated by RNAi
Here is an excellent review.
http://www.scbt.com/gene_silencers.html
I found this paper particularly fascinating
Intersection of the RNA Interference and X-Inactivation Pathways
http://www.sciencemag.org/content/320/5881/1336
Here is another
siRNA induced transcriptional gene silencing in mammalian cells.
http://www.ncbi.nlm.nih.gov/pubmed/15684610
I draw your attention to the importance of RNAi as a “gene silencer” for so-called individual oncogenes such as myc.
Promoter-specific transcriptional interference and c-myc gene silencing by siRNAs in human cells.